Multiple signaling pathways of VPC fate specification


  • C. Li*, M. Nagasaki*, K. Ueno and S. Miyano, Simulation-based Model Checking Approach to Cell Fate Determination During Caenorhabditis elegans Vulval Development by Hybrid Functional Petri Net with Extension, BMC Syst Biol., 3:42, 2009 Apr. (*These authors equally contributed to this work).

To read and download the paper, please click here.

Model for the signaling events during vulval induction

Biological diagram of the signaling pathways underlying vulval fate specification

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Download Simulation Model

CSML3.0 version: CSML.GZ | CSML [2011-02-09] (work on CIO4.0 and CIO5.0, "High-speed simulation module" is recommended)

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Supplemental DATA

  • Supplemental All parameters that were used in the VPC fate model with the csv format.
  • Supplemental source code used to obtain JA fate patterns with Mocha.

A powerpoint file briefly describing this work: explain.ppt [2008-12-25]